Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7289962 | 0.85 | TDP1 (0.56) | TDP1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7435500 | 0.80 | ALDH1A1 (0.57) | TDP1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7434236 | 0.77 | KDM4E (0.63) | TDP1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7291950 | 0.75 | CYP3A4 (0.80) | TDP1MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7444027 | 0.73 | KDM4E (0.61) | MEN1KMT2ALMNAALDH1A1CYP2C19 | |
| SCHEMBL11147641 | 0.73 | GAA (0.51) | KMT2ALMNAALDH1A1CYP2C19KDM4E | |
| SCHEMBL7434820 | 0.72 | ALDH1A1 (0.68) | MEN1KMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL7438110 | 0.71 | POLB (0.74) | MEN1KMT2ALMNAALDH1A1RAB9A | |
| SCHEMBL18998184 | 0.71 | RAB9A (0.53) | MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11847704 | 0.71 | ALDH1A1 (0.55) | MEN1KMT2ALMNAALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |