Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 13/20 | 0.37 |
| ▸ | F11 | P03951 | 2/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4807393 | 0.82 | AGER (0.39) | SMYD3 | |
| Trifluoroacetic Acid SCHEMBL7433732 | 0.81 | SLC6A2 (0.34) | OPRM1OPRD1F11KLKB1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL4810923 | 0.78 | DCUN1D1 (0.36) | OPRM1OPRD1F10 | |
| Trifluoroacetic Acid SCHEMBL4803612 | 0.76 | TPSAB1 (0.41) | OPRM1OPRD1F10 | |
| SCHEMBL7121817 | 0.76 | HSD17B3 (0.41) | OPRM1OPRD1F10 | |
| Trifluoroacetic Acid SCHEMBL7128376 | 0.76 | TRPM8 (0.37) | OPRM1OPRD1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL4810746 | 0.75 | F2 (0.38) | OPRM1OPRD1F10 | |
| Trifluoroacetic Acid SCHEMBL7430919 | 0.74 | ALDH1A1 (0.51) | SMYD3 | |
| Trifluoroacetic Acid SCHEMBL7438438 | 0.74 | ALDH1A1 (0.34) | OPRM1OPRD1SMYD3 | |
| Trifluoroacetic Acid SCHEMBL8141928 | 0.73 | ALDH1A1 (0.59) | SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1192135-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2000076970-A2 | SERINE PROTEASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2000-12-21 | — | — | WO | disclosed |
| WO-2000077027-A2 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2000-12-21 | — | — | WO | disclosed |