Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7440356 | 0.86 | POLB (0.43) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7436669 | 0.85 | ALDH1A1 (0.52) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL10997865 | 0.85 | ATM (0.51) | ATMLMNAMAPTSMN1; SMN2NPSR1 | |
| Hydrochloric Acid SCHEMBL7444391 | 0.84 | ALDH1A1 (0.52) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7434409 | 0.83 | MAPT (0.42) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| Acetic Acid SCHEMBL7435033 | 0.83 | ALDH1A1 (0.50) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7436658 | 0.81 | LMNA (0.39) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7439371 | 0.81 | LMNA (0.42) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7444380 | 0.81 | LMNA (0.39) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7432498 | 0.80 | LTA4H (0.52) | LMNAMAPTSMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |