Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436669 | 0.91 | ALDH1A1 (0.52) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7444391 | 0.90 | ALDH1A1 (0.52) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| Acetic Acid SCHEMBL7435033 | 0.89 | ALDH1A1 (0.50) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL10997887 | 0.87 | LMNA (0.46) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7440356 | 0.86 | POLB (0.43) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7435451 | 0.84 | RAB9A (0.51) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7437173 | 0.83 | ALDH1A1 (0.49) | LMNASMN1; SMN2NPSR1ALDH1A1DRD4 | |
| SCHEMBL7434405 | 0.83 | ATM (0.48) | MAPTLMNASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL7439962 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1DRD4L3MBTL1TDP1 | |
| SCHEMBL7434584 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1DRD4L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |