Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020387 | 0.92 | — | — | |
| Potassium Ion SCHEMBL10631839 | 0.87 | CA4 (0.44) | — | |
| Oxalic Acid SCHEMBL2290170 | 0.71 | CA4 (0.78) | — | |
| Glyoxylate SCHEMBL323898 | 0.70 | — | — | |
| Fumaric Acid SCHEMBL6468117 | 0.70 | CA1 (0.50) | — | |
| Fumaric Acid SCHEMBL28714104 | 0.70 | CA1 (0.50) | — | |
| Fumaric Acid SCHEMBL6468108 | 0.70 | CA1 (0.50) | — | |
| Fumaric Acid SCHEMBL105898 | 0.70 | CA1 (0.50) | — | |
| Fumaric Acid SCHEMBL105897 | 0.70 | CA1 (0.50) | — | |
| Fumaric Acid SCHEMBL5815 | 0.70 | CA1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144854-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2022-05-12 | — | — | US | disclosed |
| EP-3924358-A1 | MACROCYCLIC COMPOUNDS | Zeno Management, Inc. (US) | 2021-12-22 | — | — | EP | disclosed |
| EP-3475277-B1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-10-20 | — | — | EP | disclosed |
| US-11130741-B2 | Anti-infective heterocyclic compounds and uses thereof | BIOIMICS AB (SE) | 2021-09-28 | — | — | US | disclosed |
| WO-2021080330-A1 | NICOTINAMIDE COMPOUND AND HERBICIDAL COMPOSITION COMPRISING COMPOUND | 한국화학연구원 | 2021-04-29 | — | — | WO | disclosed |
| WO-2020185606-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. (US) | 2020-09-17 | — | — | WO | disclosed |
| US-20190233384-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2019-08-01 | — | — | US | disclosed |
| EP-3475277-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | Bioimics AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017222466-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2017-12-28 | — | — | WO | disclosed |
| WO-1994005667-A1 | CARBAPENEM DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 1994-03-17 | — | — | WO | disclosed |
| US-5116826-A | SILAZANEOPHYL SULFIDES, AND THEIR USE AS PESTICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |
| US-5037807-A | Hypotensive agents; for treatment of congestive heart failure | MERCK & CO., INC. (US) | 1991-08-06 | — | — | US | disclosed |
| US-5002957-A | Insecticides, acaricides, nematocides | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-26 | — | — | US | disclosed |
| EP-0167139-B1 | CARBAPENEMS HAVING AN EXTERNALLY ALKYLATED 2-QUATERNARY PYRIDINIUMALKYLTHIO SUBSTITUENT | MERCK & CO. INC. (US) | 1991-02-27 | — | — | EP | disclosed |
| EP-0278158-A2 | Renin inhibitors containing phenylalanyl-histidine replacements | MERCK & CO. INC. (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0167139-A1 | Carbapenems having an externally alkylated 2-quaternary pyridiniumalkylthio substituent | MERCK & CO. INC. (US) | 1986-01-08 | — | — | EP | disclosed |
| US-4413120-A | FROM L-RHAMNAL, MULTISTAGE, ANTHRACYCLINE ANTIBIOTIC INTERMEDIATES | PURDUE RESEARCH FOUNDATION (US) | 1983-11-01 | — | — | US | disclosed |