Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | CTSK | P43235 | 12/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4699482 | 0.83 | CTSL (0.68) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4698845 | 0.72 | CTSL (0.75) | CTSLCTSBCTSSCTSK | |
| SCHEMBL6208594 | 0.70 | CTSL (0.45) | CTSLCTSBCTSSCTSKHTR7 | |
| SCHEMBL3954627 | 0.69 | CYP1A2 (0.61) | CTSKPOLBALDH1A1CYP1A2 | |
| SCHEMBL1359864 | 0.69 | ADRB1 (0.76) | HTR1AHTR7USP2ALDH1A1TSHR | |
| SCHEMBL6991463 | 0.69 | TSHR (0.51) | USP2ALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL6989644 | 0.67 | ALDH1A1 (0.51) | USP2ALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL3210914 | 0.67 | CYP1A2 (0.51) | CTSKPOLBUSP2ALDH1A1HSD17B10 | |
| Trifluoroacetic Acid SCHEMBL5265518 | 0.67 | USP2 (0.59) | CTSLCTSBCTSSCTSKHTR1A | |
| Hydrochloric Acid SCHEMBL2991144 | 0.67 | CYP1A2 (0.61) | CTSKALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020156063-A1 | Arylacetamido-ketobenzoxazole as cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2002-10-24 | — | — | US | disclosed |
| WO-2002080920-A1 | ARYLACETAMIDO-KETOBENZOXAZOLE AS CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020156063-A1 | Arylacetamido-ketobenzoxazole as cysteine protease inhibitors | SERPINB1, SPINT2, PRSS1 | CTSL 34/4885CTSB 17/4885CTSS 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.