Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 13/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431884 | 0.85 | LMNA (0.48) | LTA4HMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL7431708 | 0.85 | FAAH (0.45) | MAPTSMN1; SMN2LMNANPSR1ALDH1A1 | |
| SCHEMBL7432498 | 0.85 | LTA4H (0.52) | LTA4HMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL7436536 | 0.84 | TSHR (0.48) | MAPTSMN1; SMN2LMNANPSR1MAPK1 | |
| SCHEMBL7431782 | 0.84 | SMN1; SMN2 (0.44) | LTA4HMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL7435567 | 0.83 | TEAD1 (0.46) | LTA4HHPGDKMT2AGAA | |
| SCHEMBL7444217 | 0.83 | LMNA (0.47) | LTA4HMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL7432863 | 0.83 | MAPT (0.45) | LTA4HMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL7435319 | 0.83 | EPHX1 (0.47) | LTA4HMAPTSMN1; SMN2LMNANPSR1 | |
| SCHEMBL7438055 | 0.82 | GAA (0.42) | LTA4HMAPTSMN1; SMN2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |