Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.41 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438375 | 0.90 | DRD3 (0.49) | EPHX2GAAHSD11B1PRMT5MEN1 | |
| SCHEMBL7435319 | 0.90 | EPHX1 (0.47) | EPHX2EPHX1PRMT5MEN1KMT2A | |
| SCHEMBL7436670 | 0.88 | NPC1 (0.44) | EPHX2PRMT5MGLLMEN1KMT2A | |
| SCHEMBL7438480 | 0.88 | LMNA (0.44) | EPHX2PRMT5MEN1KMT2ALTA4H | |
| SCHEMBL7440526 | 0.85 | GAA (0.46) | EPHX2GAAHSD11B1PRMT5KMT2A | |
| SCHEMBL7438639 | 0.84 | ALDH1A1 (0.47) | GAAHSD11B1MEN1KMT2AHPGD | |
| SCHEMBL7432904 | 0.83 | LTA4H (0.44) | MGLLKMT2AHPGDLTA4H | |
| SCHEMBL7434769 | 0.83 | LTA4H (0.40) | GAAKMT2AHPGDLTA4H | |
| SCHEMBL7430176 | 0.82 | TEAD1 (0.44) | TEAD1GAALTA4H | |
| SCHEMBL7431389 | 0.82 | HPGD (0.51) | MEN1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |