Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 14/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 9/20 | 0.52 |
| ▸ | HTR3B | O95264 | 9/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 9/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432574 | 0.94 | HTR3A (0.60) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7430512 | 0.93 | HTR3E (0.56) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7484945 | 0.85 | HTR3A (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7443724 | 0.82 | HTR3A (0.50) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9583246 | 0.75 | KDM4E (0.40) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7444191 | 0.71 | HTR3E (0.45) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7439911 | 0.70 | HTR3A (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7438581 | 0.70 | HTR3E (0.85) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7435237 | 0.69 | HTR3A (0.78) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL9680491 | 0.69 | HTR3A (0.54) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458636-A1 | Antiemetic and migraine suppressing heterocyclic compounds and pharmaceutical compositions containing them | KYOWA HAKKO KOGYO CO., LTD (JP) | 1991-11-27 | — | — | EP | disclosed |