Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 11/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 9/20 | 0.54 |
| ▸ | HTR3B | O95264 | 9/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 9/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 9/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | RORA | P35398 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | RORB | Q92753 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744943 | 0.79 | MEN1 (0.47) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7432574 | 0.76 | HTR3A (0.60) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7430512 | 0.73 | HTR3E (0.56) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7438581 | 0.70 | HTR3E (0.85) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7435062 | 0.70 | HTR3A (0.70) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7439804 | 0.70 | HTR3E (1.00) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7439911 | 0.70 | HTR3A (0.68) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7434788 | 0.69 | HTR3A (0.52) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL7435237 | 0.69 | HTR3A (0.78) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL10730998 | 0.69 | PGR (0.70) | NPC1PGRRORARORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096901-A | PHARMACOLOGICALLY ACTIVE AMIDES AND ESTERS CONTAINING AN AZABICYCLOALKANE MOIETY | JOHN WYETH & BROTHER LIMITED (GB) | 1992-03-17 | — | — | US | claimed |