Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 5/20 | 0.43 |
| ▸ | MMP2 | P08253 | 5/20 | 0.43 |
| ▸ | MMP13 | P45452 | 4/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421796 | 0.93 | MMP1 (0.43) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7426328 | 0.89 | MMP2 (0.40) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7434872 | 0.80 | MMP9 (0.52) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7596473 | 0.78 | MMP9 (0.51) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL9272490 | 0.73 | ALDH1A1 (0.40) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL4429590 | 0.73 | MMP9 (0.37) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7421799 | 0.73 | MMP9 (0.52) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7425774 | 0.71 | MMP9 (0.51) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7595945 | 0.71 | MMP9 (0.51) | MMP9MMP2MMP13MMP1MMP8 | |
| SCHEMBL7596477 | 0.71 | MMP9 (0.80) | MMP9MMP2MMP13MMP1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147101-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000044739-A1 | REVERSE HYDROXAMATE INHIBITORS OF MATRIX METALLOPROTEINASES | ABBOTT LABORATORIES (US) | 2000-08-03 | — | — | WO | claimed |