Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | POLB | P06746 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305254 | 0.88 | PSMB5 (0.39) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL8681327 | 0.88 | ALDH1A1 (0.34) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7434956 | 0.88 | MMP3 (0.36) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7303801 | 0.86 | ALDH1A1 (0.40) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7433585 | 0.86 | MAOB (0.35) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7305075 | 0.84 | CYP1A2 (0.42) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7311340 | 0.83 | POLB (0.40) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7299096 | 0.83 | ALDH1A1 (0.43) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7300826 | 0.83 | TAS1R3 (0.42) | ALDH1A1POLBMAPTUSP2HSD17B10 | |
| SCHEMBL7313603 | 0.83 | ALDH1A1 (0.40) | ALDH1A1POLBMAPTUSP2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |