SCHEMBL424806

SCHEMBL424806

CC(C)(Cc1ccccc1)N(N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
SLC6A2 P23975 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
CYP3A4 P08684 3/20 0.48
MEN1 O00255 2/20 0.48
CYP2C19 P33261 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 2/20 0.48
CYP2D6 P10635 2/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
SCN1A P35498 1/20 0.48
SCN2A Q99250 1/20 0.48
SCN3A Q9NY46 1/20 0.48
NPY5R Q15761 1/20 0.44
MMP8 P22894 2/20 0.44
CYP1A2 P05177 1/20 0.44
RECQL P46063 1/20 0.44
AOC3 Q16853 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2310726 0.76 MEN1 (0.49) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4
SCHEMBL9839841 0.74 HIF1A (0.53) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4
SCHEMBL7435206 0.74 CYP3A4 (0.59) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4
SCHEMBL7435200 0.73 CYP3A4 (0.57) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4
Acetic Acid SCHEMBL1551090 0.72 HIF1A (0.50) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4
SCHEMBL8759 0.72 SLC6A2 (0.56) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4
SCHEMBL6565911 0.72 TRPA1 (0.50) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4
Benzophenone SCHEMBL27920919 0.72 ALDH1A1 (0.54) HIF1ASMN1; SMN2SLC6A2TAAR1MEN1
SCHEMBL564589 0.71 BLM (0.49) HIF1ACYP3A4MEN1CYP2C19KMT2A
SCHEMBL6137883 0.71 TAAR1 (0.54) HIF1ASMN1; SMN2SLC6A2TAAR1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US claimed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US claimed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP claimed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO claimed
US-20120018088-A1 METHOD FOR CONNECTING ELECTRODES AND BONDING COMPOSITION USED THEREFOR HENKEL CORPORATION (US) 2012-01-26 US disclosed
US-7115676-B2 Adhesive compositions for bonding passive substrates HENKEL CORPORATION (US) 2006-10-03 US disclosed
US-20030217808-A1 Adhesive compositions for bonding passive substrates Henkel IP & Holding GmbH (DE) 2003-11-27 US disclosed
EP-1285037-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS Henkel Loctite Corporation (US) 2003-02-26 EP disclosed
WO-2001088050-A2 ADHESIVE COMPOSITIONS FOR BONDING PASSIVE SUBSTRATES SUCH AS MAGNESIUM ALLOYS HENKEL LOCTITE CORPORATION (US) 2001-11-22 WO disclosed
US-4321349-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1982-03-23 US disclosed
US-4287330-A Accelerator for curable compositions LOCTITE CORPORATION (US) 1981-09-01 US disclosed
US-4180640-A HYDRAZIDE DERIVATIVES LOCTITE CORPORATION (US) 1979-12-25 US disclosed