Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335056 | 0.83 | GABRA1 (0.36) | CNR1F7PARP1F3PARP10 | |
| SCHEMBL9335063 | 0.83 | GABRA1 (0.40) | F7PARP1F3PARP10NPY5R | |
| SCHEMBL8936714 | 0.81 | HSP90AA1 (0.38) | KMT2AKDM4EMAPTNPSR1ALDH1A1 | |
| SCHEMBL9338054 | 0.81 | HSD17B3 (0.38) | CNR1F7PARP1F3PARP10 | |
| SCHEMBL27273993 | 0.81 | PDE10A (0.43) | PARP1KDM4EMAPTNPSR1OPRK1 | |
| SCHEMBL7284938 | 0.79 | MAPT (0.40) | F7PARP1F3PARP10NPY5R | |
| SCHEMBL9338217 | 0.78 | ACHE (0.35) | CNR1NPY5RKMT2AGABRA1GABRG2 | |
| SCHEMBL10369849 | 0.77 | HSD17B3 (0.37) | KMT2AGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL9334812 | 0.77 | GABRA1 (0.48) | CNR1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL9334794 | 0.77 | TSHR (0.41) | KDM4EALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650966-A1 | Process for the preparation of a benzo(a)quinolizinone derivative | F. HOFFMANN-LA ROCHE AG (CH) | 1995-05-03 | — | — | EP | disclosed |