Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045991 | 0.80 | ACHE (0.50) | ACHE | |
| SCHEMBL7300493 | 0.80 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9045982 | 0.79 | ACHE (0.47) | ACHE | |
| SCHEMBL7313176 | 0.79 | — | — | |
| SCHEMBL7308473 | 0.79 | PPARG (0.54) | ACHE | |
| SCHEMBL9024785 | 0.79 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL8392990 | 0.79 | AGTR1 (0.76) | AGTR1AGTR2 | |
| SCHEMBL9044845 | 0.79 | AGTR1 (0.51) | ACHEAGTR1AGTR2 | |
| SCHEMBL7308001 | 0.78 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7307378 | 0.78 | ACHE (0.51) | ACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503785-B1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |