Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439919 | 0.81 | KMT2A (0.39) | KMT2AACEALDH1A1MEN1POLB | |
| SCHEMBL7440962 | 0.79 | HSD11B1 (0.37) | KMT2AACEALDH1A1MEN1HSD11B1 | |
| SCHEMBL7435682 | 0.78 | KMT2A (0.37) | KMT2AACEALDH1A1MEN1POLB | |
| SCHEMBL7436249 | 0.75 | ACE (0.42) | KMT2AACEALDH1A1MEN1 | |
| SCHEMBL7435787 | 0.75 | DAO (0.36) | KMT2AMEN1POLBMAPT | |
| SCHEMBL7435674 | 0.71 | CHRM1 (0.36) | KMT2AACEALDH1A1MEN1POLB | |
| SCHEMBL7425893 | 0.70 | KMT2A (0.44) | KMT2AALDH1A1MEN1HSD11B1POLB | |
| SCHEMBL7432535 | 0.69 | HSD11B1 (0.45) | KMT2AALDH1A1MEN1HSD11B1NPSR1 | |
| SCHEMBL7434183 | 0.68 | ALDH1A1 (0.37) | KMT2AALDH1A1MEN1HSD11B1POLB | |
| SCHEMBL7445427 | 0.67 | ALDH1A1 (0.41) | KMT2AACEALDH1A1MEN1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |