Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AIMP2 | Q13155 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436669 | 0.89 | ALDH1A1 (0.52) | AIMP2DRD4ALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL7444391 | 0.89 | ALDH1A1 (0.52) | AIMP2DRD4ALDH1A1MAPTLMNA | |
| SCHEMBL7437784 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTMAPK1LMNA | |
| SCHEMBL7435917 | 0.88 | POLB (0.48) | AIMP2DRD4ALDH1A1MAPTMAPK1 | |
| SCHEMBL7438055 | 0.87 | GAA (0.42) | AIMP2ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL7443888 | 0.87 | POLB (0.48) | ALDH1A1KDM4EMAPTMAPK1LMNA | |
| SCHEMBL7447951 | 0.87 | DRD4 (0.50) | AIMP2DRD4ALDH1A1KDM4EMAPT | |
| Acetic Acid SCHEMBL7435033 | 0.87 | ALDH1A1 (0.50) | DRD4ALDH1A1MAPTMAPK1LMNA | |
| SCHEMBL10993020 | 0.86 | AIMP2 (0.54) | AIMP2DRD4ALDH1A1KDM4EMAPT | |
| SCHEMBL7435451 | 0.86 | RAB9A (0.51) | DRD4ALDH1A1MAPTLMNALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | claimed |
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |