Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7435958 | 1.00 | EPHX2 (0.39) | EPHX2NR1H4PPARAPPARGALDH1A1 | |
| SCHEMBL7442363 | 0.89 | CTSK (0.43) | ALDH1A1CTSKMAPT | |
| SCHEMBL7442344 | 0.89 | CTSK (0.43) | ALDH1A1CTSKMAPT | |
| SCHEMBL7437324 | 0.88 | CTSK (0.33) | EPHX2NR1H4ALDH1A1CTSKMAPT | |
| SCHEMBL7437313 | 0.88 | CTSK (0.33) | EPHX2NR1H4ALDH1A1CTSKMAPT | |
| SCHEMBL7440833 | 0.87 | L3MBTL1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL7440856 | 0.87 | L3MBTL1 (0.40) | ALDH1A1MAPT | |
| SCHEMBL7443186 | 0.82 | ALDH1A1 (0.43) | EPHX2ALDH1A1POLB | |
| SCHEMBL7443195 | 0.82 | ALDH1A1 (0.43) | EPHX2ALDH1A1POLB | |
| SCHEMBL7445420 | 0.81 | EPHX2 (0.38) | EPHX2NR1H4PPARAPPARGOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |