Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437313 | 1.00 | CTSK (0.33) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7442363 | 0.89 | CTSK (0.43) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7442344 | 0.89 | CTSK (0.43) | CTSKMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7435950 | 0.88 | EPHX2 (0.39) | CTSKALDH1A1MAPTEPHX2NR1H4 | |
| SCHEMBL7435958 | 0.88 | EPHX2 (0.39) | CTSKALDH1A1MAPTEPHX2NR1H4 | |
| SCHEMBL7440856 | 0.85 | L3MBTL1 (0.40) | MEN1ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL7440833 | 0.85 | L3MBTL1 (0.40) | MEN1ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL7434161 | 0.81 | TPSAB1 (0.32) | EPHX2 | |
| SCHEMBL7443195 | 0.81 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AEPHX2HPGD | |
| SCHEMBL7443186 | 0.81 | ALDH1A1 (0.43) | MEN1ALDH1A1KMT2AEPHX2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |