Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442363 | 1.00 | CTSK (0.43) | CTSKALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7437313 | 0.89 | CTSK (0.33) | CTSKALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7437324 | 0.89 | CTSK (0.33) | CTSKALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7435950 | 0.89 | EPHX2 (0.39) | CTSKALDH1A1MAPT | |
| SCHEMBL7435958 | 0.89 | EPHX2 (0.39) | CTSKALDH1A1MAPT | |
| SCHEMBL7443186 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7443195 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL7440833 | 0.86 | L3MBTL1 (0.40) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7440856 | 0.86 | L3MBTL1 (0.40) | ALDH1A1MAPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL7449263 | 0.85 | OPRM1 (0.44) | ALDH1A1MAPTMEN1KMT2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187905-B1 | PEPTIDE COMPOUND WHICH INHIBITS VIRAL PROTEINASES; VIRICIDES FOR HEPATITIS C, HEPATITIS G, AND HUMAN GB VIRUSES | HOFFMANN-LA ROCHE INC. | 2001-02-13 | — | — | US | disclosed |