Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553726 | 0.91 | SIGMAR1 (0.56) | SIGMAR1 | |
| SCHEMBL1588028 | 0.83 | SIGMAR1 (0.66) | SIGMAR1 | |
| SCHEMBL7437691 | 0.82 | SIGMAR1 (0.82) | SIGMAR1OPRL1 | |
| SCHEMBL8553729 | 0.80 | SIGMAR1 (0.48) | SIGMAR1 | |
| SCHEMBL466857 | 0.80 | HTR1A (0.65) | SIGMAR1OPRL1 | |
| SCHEMBL7435097 | 0.80 | SIGMAR1 (0.83) | SIGMAR1OPRL1GRIN2B | |
| SCHEMBL7431242 | 0.80 | HTR1A (0.56) | OPRL1 | |
| SCHEMBL7431429 | 0.79 | HTR1A (0.64) | SIGMAR1OPRL1 | |
| SCHEMBL6198931 | 0.79 | HTR1A (0.64) | SIGMAR1OPRL1 | |
| SCHEMBL7440266 | 0.79 | HTR1A (0.55) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207677-B1 | ADMINISERING SIGMA RECEPTOR BINDING PIPERIDINE DERIVATIVE FOR TREATING ANXIETY, EPILEPSY, CONVULSION, MOVEMENT DISORDER, AMNESIA | H. LUNDBECK A/S (DK) | 2001-03-27 | — | — | US | disclosed |
| US-6031099-A | Piperidine derivates having anxiolytic effect | H. LUNDBECK A/S (DK) | 2000-02-29 | — | — | US | disclosed |
| US-5807871-A | PSYCHOLOGICAL DISORDERS, ALZHEIMER OR PARKINSON DISEASE | H. LUNDBECK A/S (DK) | 1998-09-15 | — | — | US | disclosed |
| EP-0859004-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-08-19 | — | — | EP | disclosed |
| EP-0853085-A1 | Piperidine derivatives having anxiolytic effect | H. LUNDBECK A/S (DK) | 1998-07-15 | — | — | EP | disclosed |
| US-5665725-A | Piperidine derivatives having anxiolytic effect | Lundbeck, H. (DK) | 1997-09-09 | — | — | US | disclosed |
| EP-0518805-A1 | Piperidine derivatives | H. LUNDBECK A/S (DK) | 1992-12-16 | — | — | EP | disclosed |