Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446446 | 0.84 | CTSL (0.38) | HTR2CSLC6A4CTSLALDH1A1GHSR | |
| SCHEMBL7443228 | 0.84 | HTR2C (0.38) | HTR2CSLC6A4CTSLCACNA1BFKBP1A | |
| SCHEMBL7435675 | 0.83 | MAPT (0.37) | GHSRCYP2C9CYP2C19NPSR1 | |
| SCHEMBL7433678 | 0.81 | GHSR (0.37) | GHSRCYP2C9CYP2C19NPSR1 | |
| SCHEMBL7433296 | 0.80 | CACNA1B (0.32) | CTSLCACNA1BGHSRNPSR1 | |
| SCHEMBL7442699 | 0.80 | MAPT (0.35) | GHSRNPSR1 | |
| SCHEMBL7441596 | 0.79 | GHSR (0.34) | ALDH1A1GHSRNPSR1 | |
| SCHEMBL7441953 | 0.79 | GHSR (0.35) | CACNA1BGHSRRAB9A | |
| SCHEMBL7441643 | 0.78 | CCKAR (0.34) | SLC6A4ALDH1A1GHSRNPSR1 | |
| SCHEMBL7431147 | 0.78 | MAPT (0.40) | ALDH1A1GHSRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |