Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436797 | 0.84 | HTR2C (0.36) | HTR2CSLC6A4CTSLCACNA1BADORA3 | |
| SCHEMBL7438701 | 0.82 | CYP1A2 (0.48) | CYP2C9CYP2C19SYK | |
| SCHEMBL7431022 | 0.81 | CYP1A2 (0.47) | CYP2C9CYP2C19 | |
| SCHEMBL7436456 | 0.79 | LTA4H (0.34) | CTSLCACNA1BADORA3ADORA2AADORA2B | |
| SCHEMBL7437714 | 0.79 | CYP1A2 (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL7434047 | 0.79 | CYP1A2 (0.36) | CYP2C9CYP2C19SYK | |
| SCHEMBL7443562 | 0.79 | CYP2C9 (0.36) | CYP2C9CYP2C19SYK | |
| SCHEMBL7440427 | 0.78 | SMN1; SMN2 (0.44) | CYP2C9CYP2C19 | |
| SCHEMBL7439049 | 0.78 | CYP1A2 (0.36) | CACNA1BCYP2C9CYP2C19SYK | |
| SCHEMBL7436644 | 0.77 | CYP1A2 (0.35) | CYP2C9CYP2C19SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710153-A | INTERLEUKIN CONVERTING ENZYME INHIBITORS | ONO PHRAMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0761680-A2 | Tetrazole compounds having Interleukin-1beta converting enzyme inhibitory activity | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-12 | — | — | EP | disclosed |