Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL335962 | 0.81 | MAPT (0.45) | TP53MAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL10613988 | 0.80 | TP53 (0.49) | TP53MAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL6569152 | 0.78 | TSHR (0.57) | TP53MAPTCYP3A4MEN1KMT2A | |
| SCHEMBL11667952 | 0.76 | LMNA (0.50) | TP53MAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL4086031 | 0.76 | TP53 (0.52) | TP53MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL959111 | 0.75 | CTSD (0.47) | TP53MAPTMEN1LMNAKMT2A | |
| SCHEMBL2212947 | 0.75 | TP53 (0.44) | TP53MAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL20133760 | 0.75 | TP53 (0.42) | TP53MAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL11144881 | 0.74 | TSHR (0.45) | TP53MAPTCYP3A4MEN1NR1I2 | |
| SCHEMBL341842 | 0.74 | TP53 (0.46) | TP53TSHRALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001030745-A1 | ANTHRANILIC ACID DERIVATIVES AS INHIBITORS OF THE CGMP-PHOSPHODIESTERASE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-03 | — | — | WO | disclosed |