Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 4/20 | 0.58 |
| ▸ | ATP4B | P51164 | 4/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.49 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.49 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437601 | 0.78 | ATP4A (0.54) | ATP4AATP4BHRH3LTA4HPRKAB2 | |
| SCHEMBL7436848 | 0.77 | ATP4A (0.56) | ATP4AATP4BHRH3LTA4HPRKAB2 | |
| Hydrochloric Acid SCHEMBL7440865 | 0.77 | ATP4A (0.55) | ATP4AATP4BHRH3LTA4HPRKAB2 | |
| Hydrochloric Acid SCHEMBL7443354 | 0.76 | ATP4A (0.57) | ATP4AATP4BHRH3LTA4HPRKAB2 | |
| SCHEMBL7437613 | 0.76 | ATP4A (0.54) | ATP4AATP4BHRH3LTA4HPRKAB2 | |
| SCHEMBL3612018 | 0.76 | ACHE (0.57) | ATP4AATP4BHRH3LTA4HPRKAB2 | |
| SCHEMBL227297 | 0.75 | HRH3 (0.85) | HRH3HRH2HRH1LTA4HPSMB1 | |
| Hydrochloric Acid SCHEMBL7440874 | 0.75 | ATP4A (0.55) | ATP4AATP4BHRH3LTA4HPRKAB2 | |
| SCHEMBL4874490 | 0.74 | HRH3 (0.82) | HRH3HRH2HRH1LTA4HPSMB1 | |
| SCHEMBL10660429 | 0.74 | ATP4A (1.00) | ATP4AATP4BHRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506194-B1 | 4-aryl-thiazole or imidazole derivatives | AKZO NOBEL NV (NL) | 1996-08-21 | — | — | EP | disclosed |
| US-5462959-A | 4-aryl-imidazole derivatives | AKZO N.V. (NL) | 1995-10-31 | — | — | US | disclosed |
| US-5254575-A | 4-aryl-thiazole derivatives | AKZO N.V. (NL) | 1993-10-19 | — | — | US | disclosed |
| EP-0506194-A1 | 4-aryl-thiazole or imidazole derivatives | Akzo Nobel N.V. (NL) | 1992-09-30 | — | — | EP | disclosed |