Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434588 | 0.83 | PPARG (0.36) | PTGIRMMP8CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL7439214 | 0.82 | MME (0.52) | PTGIRMMP8CYP2C9KMT2AMME | |
| SCHEMBL7437456 | 0.80 | ACE (0.39) | PTGIRCYP2C9KMT2AMMEPTGER4 | |
| SCHEMBL7428167 | 0.76 | MMP8 (0.43) | MMP8KMT2AMMECYP3A4 | |
| SCHEMBL7435520 | 0.73 | MME (0.41) | KMT2AMME | |
| SCHEMBL7431662 | 0.72 | KMT2A (0.53) | KMT2A | |
| SCHEMBL7433554 | 0.71 | CTSL (0.40) | MMP8MME | |
| SCHEMBL7432590 | 0.70 | HTT (0.53) | KMT2A | |
| SCHEMBL7354156 | 0.69 | KMT2A (0.55) | KMT2ACYP3A4 | |
| SCHEMBL7351604 | 0.69 | MMP8 (0.39) | PTGIRMMP8CYP2C9CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |