Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439214 | 0.90 | MME (0.52) | MMEKMT2A | |
| SCHEMBL7434571 | 0.86 | ADAM17 (0.37) | ADAM17TSHR | |
| SCHEMBL7431662 | 0.80 | KMT2A (0.53) | KMT2ACTSL | |
| SCHEMBL7428167 | 0.80 | MMP8 (0.43) | MMETSHRKMT2AALOX15 | |
| SCHEMBL7434646 | 0.79 | CTSC (0.37) | ADAM17TSHRKMT2A | |
| SCHEMBL7354156 | 0.77 | KMT2A (0.55) | TSHRKMT2AALOX15 | |
| SCHEMBL7433554 | 0.75 | CTSL (0.40) | MMECTSL | |
| SCHEMBL9414191 | 0.74 | MME (0.52) | MMEKMT2A | |
| SCHEMBL7444104 | 0.73 | CTSK (0.46) | CTSL | |
| SCHEMBL7437445 | 0.73 | PTGIR (0.38) | MMEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |