Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434571 | 0.91 | ADAM17 (0.37) | POLBMAPTS1PR4SMN1; SMN2MAPK1 | |
| SCHEMBL7434646 | 0.91 | CTSC (0.37) | CTSBCTSSPOLBMAPTSMN1; SMN2 | |
| SCHEMBL7428167 | 0.87 | MMP8 (0.43) | MMESMN1; SMN2MMP8 | |
| SCHEMBL7433267 | 0.85 | CTSL (0.54) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7341910 | 0.85 | MEN1 (0.42) | POLBMAPTS1PR4SMN1; SMN2MAPK1 | |
| SCHEMBL7439214 | 0.84 | MME (0.52) | MMEMMP8 | |
| SCHEMBL7344352 | 0.84 | NMBR (0.57) | MAPT | |
| SCHEMBL9599593 | 0.83 | TACR2 (0.38) | CTSLCTSBCTSSPOLBMAPT | |
| SCHEMBL7434588 | 0.83 | PPARG (0.36) | CTSLCTSBCTSSPOLBMAPT | |
| SCHEMBL7351604 | 0.83 | MMP8 (0.39) | MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5208964-A | — | — | None | — | — | JP | disclosed |
| US-5312826-A | Dicarboxylic acids with hypotensive agents and cardiovascular disorders | TANABE SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| JP-H05208964-A | DICARBOXYLIC ACID AND ITS PRODUCTION | TANABE SEIYAKU CO LTD | 1993-08-20 | — | — | JP | disclosed |
| EP-0519738-A1 | Dicarboxylic acid derivatives and process for preparation thereof | TANABE SEIYAKU CO., LTD. (JP) | 1992-12-23 | — | — | EP | disclosed |