Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645683 | 0.80 | HSD17B10 (0.49) | SRD5A2MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL7437658 | 0.79 | ALDH1A1 (0.50) | SRD5A2MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL27626953 | 0.76 | ALDH1A1 (0.54) | MAPTLMNASMN1; SMN2NPC1GAA | |
| SCHEMBL571045 | 0.74 | CA12 (0.63) | MAPTLMNASMN1; SMN2TDP1MEN1 | |
| SCHEMBL28907645 | 0.74 | ALDH1A1 (0.51) | MAPTLMNASMN1; SMN2TDP1NPC1 | |
| SCHEMBL6172186 | 0.74 | ALDH1A1 (0.48) | SRD5A2MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL164673 | 0.73 | TSHR (0.52) | MAPTLMNASMN1; SMN2TDP1NR1H4 | |
| SCHEMBL6108635 | 0.72 | PPARG (0.58) | MAPTLMNANR1H4MEN1RAB9A | |
| SCHEMBL28222952 | 0.71 | TSHR (0.57) | MAPTLMNASMN1; SMN2MEN1NPC1 | |
| SCHEMBL7126704 | 0.71 | LMNA (0.58) | MAPTLMNASMN1; SMN2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140903-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039118-A1 | AROMATIC AMIDES | ELI LILLY AND COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |