Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7436003 | 0.93 | HDAC6 (0.42) | MAPTMEN1KMT2AUSP2L3MBTL1 | |
| SCHEMBL7428792 | 0.88 | CYP2D6 (0.45) | KMT2AENPP2POLBNPSR1 | |
| SCHEMBL7432645 | 0.83 | ENPP2 (0.47) | MAPTMEN1KMT2AUSP2L3MBTL1 | |
| SCHEMBL7435811 | 0.82 | ACHE (0.41) | MAPTMEN1KMT2AUSP2L3MBTL1 | |
| SCHEMBL7445702 | 0.79 | ACHE (0.40) | MAPTMEN1KMT2AUSP2L3MBTL1 | |
| SCHEMBL7426519 | 0.78 | MME (0.42) | MAPTMEN1KMT2AUSP2L3MBTL1 | |
| SCHEMBL7428456 | 0.78 | PLA2G10 (0.45) | KDM4EENPP2SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL7440468 | 0.76 | POLB (0.37) | MAPTMEN1KMT2AUSP2L3MBTL1 | |
| SCHEMBL7446529 | 0.76 | ACE (0.41) | MEN1KMT2AHTTTSHRSMN1; SMN2 | |
| SCHEMBL7440735 | 0.75 | L3MBTL1 (0.42) | MEN1KMT2AL3MBTL1GAAENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |