Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.45 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428792 | 0.84 | CYP2D6 (0.45) | NPSR1ENPP2POLBACE | |
| SCHEMBL7428452 | 0.81 | PLA2G10 (0.45) | PLA2G10PLA2G5CTSSCTSKENPP2 | |
| SCHEMBL7445702 | 0.81 | ACHE (0.40) | NPSR1ENPP2ALDH1A1KDM4EPOLB | |
| SCHEMBL7432645 | 0.78 | ENPP2 (0.47) | NPSR1ENPP2ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7426522 | 0.78 | MAPT (0.43) | NPSR1ENPP2ALDH1A1KDM4EPOLB | |
| SCHEMBL7440468 | 0.78 | POLB (0.37) | NPSR1ALDH1A1POLBHSD17B2SMN1; SMN2 | |
| SCHEMBL7436003 | 0.76 | HDAC6 (0.42) | ENPP2KDM4EPOLBACESMN1; SMN2 | |
| SCHEMBL7737652 | 0.74 | PLA2G10 (0.50) | PLA2G10PLA2G5ALDH1A1KDM4EPOLB | |
| SCHEMBL7435811 | 0.74 | ACHE (0.41) | ENPP2KDM4EPOLBHSD17B2ACE | |
| SCHEMBL7446529 | 0.73 | ACE (0.41) | NPSR1ALDH1A1POLBACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |