Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994604 | 0.78 | DRD2 (0.58) | SLC6A3DRD2DRD4DRD3TACR1 | |
| SCHEMBL7429491 | 0.77 | TAAR1 (0.41) | SLC6A3DRD2DRD4DRD3TACR1 | |
| SCHEMBL27504852 | 0.72 | POLQ (0.42) | SLC6A3DRD2SLC6A2SLC6A4DAO | |
| SCHEMBL21123197 | 0.70 | TAAR1 (0.58) | SLC6A2SLC6A4DAOTAAR1AOC3 | |
| SCHEMBL7434179 | 0.69 | SLC6A3 (0.49) | SLC6A3DRD2DRD4DRD3SLC6A2 | |
| SCHEMBL17329111 | 0.67 | IDO1 (0.59) | SLC6A2SLC6A4DAOPOLQ | |
| SCHEMBL5199196 | 0.66 | TAAR1 (0.54) | DAOTAAR1AOC3 | |
| SCHEMBL27504853 | 0.66 | POLQ (0.41) | SLC6A3SLC6A2SLC6A4DAOTAAR1 | |
| SCHEMBL8030461 | 0.64 | SLC6A2 (0.48) | SLC6A3SLC6A2SLC6A4TACR1DAO | |
| SCHEMBL15080035 | 0.62 | MAOB (0.51) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171752-A | BENZHYDRYL DERIVATIVES HAVING CALMODULIN INHIBITOR PROPERTIES | AKZO N.V. (NL) | 1992-12-15 | — | — | US | disclosed |
| EP-0467435-A2 | Benzhydryl derivatives having calmodulin inhibitor properties | Akzo Nobel N.V. (NL) | 1992-01-22 | — | — | EP | disclosed |