Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498395 | 0.79 | DRD2 (0.59) | TAAR1DRD2DRD4DRD3SLC6A3 | |
| SCHEMBL7438508 | 0.77 | SLC6A3 (0.39) | TAAR1DRD2DRD4DRD3SLC6A3 | |
| SCHEMBL169714 | 0.71 | TAAR1 (0.61) | TAAR1DRD3MEN1LMNAKMT2A | |
| SCHEMBL7371773 | 0.69 | SIGMAR1 (0.68) | TAAR1SIGMAR1 | |
| SCHEMBL10682043 | 0.66 | TAAR1 (0.57) | TAAR1DRD2DRD3SLC6A3MEN1 | |
| Trifluoromethylbenzene SCHEMBL8846975 | 0.65 | DRD2 (0.56) | DRD2DRD4DRD3SLC6A3 | |
| SCHEMBL1551304 | 0.64 | LTA4H (0.54) | TAAR1LMNAGAAHTR2AHTR2C | |
| SCHEMBL429769 | 0.63 | TAAR1 (0.67) | TAAR1DRD3LMNAGAAHTR2A | |
| SCHEMBL30876859 | 0.63 | TAAR1 (0.67) | TAAR1DRD3LMNAGAAHTR2A | |
| SCHEMBL587871 | 0.63 | TAAR1 (0.57) | TAAR1DRD2DRD3SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171752-A | BENZHYDRYL DERIVATIVES HAVING CALMODULIN INHIBITOR PROPERTIES | AKZO N.V. (NL) | 1992-12-15 | — | — | US | disclosed |
| EP-0467435-A2 | Benzhydryl derivatives having calmodulin inhibitor properties | Akzo Nobel N.V. (NL) | 1992-01-22 | — | — | EP | disclosed |