Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2794665 | 0.82 | MEN1 (0.56) | SIGMAR1CYP2D6MEN1KMT2ASLC6A2 | |
| SCHEMBL336219 | 0.74 | CYP2D6 (0.67) | SIGMAR1CYP2D6CYP19A1ACHEMEN1 | |
| SCHEMBL4094720 | 0.69 | HTR7 (0.39) | SIGMAR1SLC6A2SLC6A4SLC6A3HTR7 | |
| SCHEMBL16225886 | 0.69 | MEN1 (0.79) | CYP2D6CYP19A1MEN1KMT2AOPRM1 | |
| SCHEMBL1138318 | 0.69 | MEN1 (0.79) | CYP2D6CYP19A1MEN1KMT2AOPRM1 | |
| SCHEMBL7438580 | 0.69 | MEN1 (0.44) | SIGMAR1CYP2D6MEN1KMT2ASLC6A2 | |
| SCHEMBL7427630 | 0.69 | CYP2D6 (0.59) | SIGMAR1CYP2D6CYP19A1ACHEMEN1 | |
| SCHEMBL1138320 | 0.69 | MEN1 (0.79) | CYP2D6CYP19A1MEN1KMT2AOPRM1 | |
| SCHEMBL8182035 | 0.68 | CYP2D6 (0.57) | CYP2D6CYP19A1ACHEMEN1KMT2A | |
| SCHEMBL21831877 | 0.67 | SIGMAR1 (0.39) | SIGMAR1CYP2D6CYP19A1ACHESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266549-B1 | CINNAMYL AMINES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-06-19 | — | — | EP | claimed |