Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438517 | 0.80 | GAA (0.35) | HSD11B1P2RX7NPC1RAB9AEPHX2 | |
| SCHEMBL7438509 | 0.71 | CPA3 (0.37) | HSD11B1ALDH1A1HPGD | |
| SCHEMBL7435682 | 0.62 | KMT2A (0.37) | CNR1CNR2ALDH1A1ACENPSR1 | |
| SCHEMBL7431861 | 0.62 | CNR2 (0.33) | NPC1CNR2GAAALDH1A1NPSR1 | |
| SCHEMBL7188715 | 0.61 | KMT2A (0.56) | NPC1RAB9ACNR2MAPK1SMN1; SMN2 | |
| SCHEMBL7432509 | 0.61 | TSHR (0.33) | CNR2GAAALDH1A1ACENPSR1 | |
| SCHEMBL7307985 | 0.60 | ACE (0.47) | CNR2SMN1; SMN2ALDH1A1ACEHPGD | |
| SCHEMBL7307992 | 0.60 | ACE (0.47) | CNR2SMN1; SMN2ALDH1A1ACEHPGD | |
| SCHEMBL13970215 | 0.60 | ALDH1A1 (0.43) | NPC1RAB9ACNR1CNR2MAPK1 | |
| SCHEMBL15989073 | 0.60 | CYP19A1 (0.48) | HSD11B1P2RX7NPC1RAB9AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |