Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438774 | 0.80 | HSD11B1 (0.35) | GAAMAPK1SMN1; SMN2HSD11B1P2RX7 | |
| SCHEMBL7438509 | 0.79 | CPA3 (0.37) | HSD11B1POLBMAPTOPRK1ALDH1A1 | |
| SCHEMBL7432468 | 0.77 | HSD11B1 (0.46) | GAAMAPK1SMN1; SMN2HSD11B1EPHX2 | |
| SCHEMBL7431861 | 0.76 | CNR2 (0.33) | GAANPC1POLBMEN1KMT2A | |
| SCHEMBL7432509 | 0.75 | TSHR (0.33) | GAAPOLBMEN1KMT2AUSP2 | |
| SCHEMBL7426794 | 0.74 | POLB (0.37) | GAAMAPK1POLBMEN1KMT2A | |
| SCHEMBL7432645 | 0.74 | ENPP2 (0.47) | GAASMN1; SMN2EPHX2POLBMEN1 | |
| SCHEMBL7435831 | 0.72 | ACHE (0.40) | GAAPOLBMEN1KMT2AUSP2 | |
| SCHEMBL7425893 | 0.72 | KMT2A (0.44) | SMN1; SMN2HSD11B1RAB9APOLBMEN1 | |
| SCHEMBL7442890 | 0.71 | ACE (0.40) | GAAMAPK1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |