Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431861 | 0.99 | CNR2 (0.33) | CNR2ALDH1A1PKMPOLBNPSR1 | |
| SCHEMBL7432501 | 0.80 | CPA3 (0.41) | ALDH1A1PKMPOLBKMT2AMEN1 | |
| SCHEMBL7431854 | 0.79 | CPA3 (0.42) | ALDH1A1PKMPOLBKMT2AMEN1 | |
| SCHEMBL7438517 | 0.75 | GAA (0.35) | TSHRALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL7428792 | 0.74 | CYP2D6 (0.45) | POLBNPSR1KMT2AACE | |
| SCHEMBL7436715 | 0.73 | SIGMAR1 (0.37) | POLBKMT2AMEN1USP2GAA | |
| SCHEMBL7426522 | 0.72 | MAPT (0.43) | TSHRALDH1A1POLBNPSR1KMT2A | |
| SCHEMBL7440468 | 0.72 | POLB (0.37) | TSHRCNR2ALDH1A1PKMPOLB | |
| SCHEMBL7432535 | 0.72 | HSD11B1 (0.45) | ALDH1A1NPSR1KMT2AMEN1HTT | |
| SCHEMBL7446529 | 0.72 | ACE (0.41) | TSHRALDH1A1PKMPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |