Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11096282 | 0.85 | ALDH1A1 (0.59) | KMT2AALDH1A1SMN1; SMN2DRD2HTR2A | |
| SCHEMBL16799143 | 0.76 | PDE4B (0.47) | BRD4KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL7435812 | 0.74 | SIGMAR1 (0.56) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL11095969 | 0.74 | POLB (0.50) | KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10555303 | 0.74 | CYP2C9 (0.50) | KMT2AALDH1A1DRD2HTR2AHTR2C | |
| SCHEMBL15537093 | 0.73 | KMT2A (0.58) | KMT2AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL13451670 | 0.73 | BRD4 (0.50) | BRD4 | |
| SCHEMBL7446326 | 0.72 | MAOB (0.50) | KMT2ADRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7446022 | 0.72 | ALDH1A1 (0.67) | ALDH1A1 | |
| SCHEMBL20601445 | 0.72 | KDM4E (0.68) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020928-A1 | PIPERIDINE-BASED SIGMA RECEPTOR LIGANDS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 1996-07-11 | — | — | WO | disclosed |