Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446022 | 0.78 | ALDH1A1 (0.67) | — | |
| SCHEMBL11096282 | 0.77 | ALDH1A1 (0.59) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7438856 | 0.74 | BRD4 (0.46) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7446326 | 0.73 | MAOB (0.50) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL11093812 | 0.72 | P2RX7 (0.56) | DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL10555303 | 0.72 | CYP2C9 (0.50) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL11125603 | 0.72 | MAOB (0.49) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL7358803 | 0.71 | SIGMAR1 (1.00) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL22804710 | 0.71 | DRD2 (0.50) | SIGMAR1DRD2HTR2A | |
| SCHEMBL7382476 | 0.71 | DRD2 (0.64) | SIGMAR1DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020928-A1 | PIPERIDINE-BASED SIGMA RECEPTOR LIGANDS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 1996-07-11 | — | — | WO | disclosed |