Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441662 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4ETHRBATMLMNA | |
| SCHEMBL7438879 | 0.78 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAPOLBTSHR | |
| SCHEMBL7434820 | 0.78 | ALDH1A1 (0.68) | ALDH1A1KDM4ETHRBATMLMNA | |
| SCHEMBL7437444 | 0.77 | KMT2A (0.64) | ALDH1A1KDM4ETHRBPOLBTSHR | |
| SCHEMBL7426498 | 0.77 | ME2 (0.58) | ALDH1A1KDM4ETHRBATMLMNA | |
| SCHEMBL15587815 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4ETHRBATMPOLB | |
| SCHEMBL7440438 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KDM4EATMLMNAMAPT | |
| SCHEMBL7441384 | 0.75 | CA1 (0.58) | ALDH1A1KDM4ETHRBATMLMNA | |
| SCHEMBL7445611 | 0.74 | POLB (0.59) | ALDH1A1LMNAPOLBTSHRCYP1A2 | |
| SCHEMBL7445763 | 0.74 | LMNA (0.69) | ALDH1A1KDM4ELMNAPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |