Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 3/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442303 | 0.85 | ALDH1A1 (0.53) | KMT2ACYP2C19PKMMEN1MAPT | |
| SCHEMBL7439151 | 0.78 | MME (0.46) | PKMMAPTGAASMN1; SMN2 | |
| SCHEMBL2443777 | 0.76 | DNMT1 (0.73) | DNMT1STAT3KMT2ACYP2C19DNMT3B | |
| SCHEMBL19244073 | 0.76 | DNMT1 (0.73) | DNMT1STAT3KMT2ACYP2C19DNMT3B | |
| SCHEMBL7446522 | 0.75 | CPA3 (0.44) | PKMMAPTSMN1; SMN2 | |
| SCHEMBL3081901 | 0.75 | DNMT1 (0.75) | DNMT1STAT3KMT2ACYP2C19DNMT3B | |
| SCHEMBL4214992 | 0.75 | DNMT1 (0.75) | DNMT1STAT3KMT2ACYP2C19DNMT3B | |
| SCHEMBL2445932 | 0.75 | DNMT1 (0.75) | DNMT1STAT3KMT2ACYP2C19DNMT3B | |
| SCHEMBL1984728 | 0.75 | DNMT1 (0.75) | DNMT1STAT3KMT2ACYP2C19DNMT3B | |
| SCHEMBL23683013 | 0.73 | DNMT1 (1.00) | DNMT1STAT3KMT2ACYP2C19DNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640594-A1 | Hydantoin derivative as metalloprotease inhibitor | FUJIREBIO INC. (JP) | 1995-03-01 | — | — | EP | disclosed |