Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431674 | 0.88 | LMNA (0.42) | NPC1LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7439458 | 0.86 | MAPT (0.40) | LMNAKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7429333 | 0.86 | MAPT (0.37) | NPC1LMNASMN1; SMN2MAPTNPSR1 | |
| SCHEMBL7443120 | 0.85 | LMNA (0.41) | NPC1LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7428117 | 0.85 | LMNA (0.43) | NPC1LMNAL3MBTL1ALDH1A1HPGD | |
| SCHEMBL7433758 | 0.84 | NPC1 (0.38) | NPC1LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL7441214 | 0.84 | GAA (0.41) | NPC1LMNAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7440244 | 0.84 | ADRB2 (0.38) | LMNAKDM4EALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7440221 | 0.83 | ALDH1A1 (0.47) | NPC1LMNAL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7434347 | 0.83 | MAPT (0.37) | LMNAALDH1A1SMN1; SMN2MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |