Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7431674 | 0.92 | LMNA (0.42) | LMNANPC1ALDH1A1HPGDCHRM2 | |
| SCHEMBL7434217 | 0.91 | ADRB3 (0.38) | LMNANPC1MCHR1FFAR1MAPT | |
| SCHEMBL7436565 | 0.89 | ALDH1A1 (0.39) | LMNAALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL7439458 | 0.89 | MAPT (0.40) | LMNAALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL7446102 | 0.89 | LMNA (0.39) | LMNANPC1ALDH1A1HPGDALOX5 | |
| SCHEMBL7437776 | 0.88 | LMNA (0.38) | LMNANPC1ALDH1A1HPGDMCHR1 | |
| SCHEMBL7435692 | 0.88 | LMNA (0.37) | LMNANPC1CHRM2CHRM1MCHR1 | |
| SCHEMBL7431667 | 0.87 | LMNA (0.37) | LMNANPC1ALDH1A1HPGDMCHR1 | |
| SCHEMBL7434853 | 0.86 | MTNR1A (0.40) | LMNANPC1ALDH1A1HPGDMCHR1 | |
| SCHEMBL10992545 | 0.86 | LMNA (0.43) | LMNANPC1ALDH1A1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |