Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437962 | 0.88 | POLB (0.47) | ALDH1A1CYP1A2KDM4EL3MBTL1TSHR | |
| SCHEMBL7441435 | 0.87 | L3MBTL1 (0.43) | ALDH1A1CYP1A2KDM4EHTTL3MBTL1 | |
| SCHEMBL7440526 | 0.87 | GAA (0.46) | ALDH1A1HTTL3MBTL1KMT2AGAA | |
| SCHEMBL7431440 | 0.86 | KDM4E (0.48) | ALDH1A1CYP1A2KDM4EMEN1CYP3A4 | |
| SCHEMBL7431439 | 0.86 | KDM4E (0.48) | ALDH1A1CYP1A2KDM4EMEN1CYP3A4 | |
| SCHEMBL7435319 | 0.85 | EPHX1 (0.47) | ALDH1A1MAPK1MEN1CYP2C19KMT2A | |
| SCHEMBL7438480 | 0.84 | LMNA (0.44) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7439160 | 0.83 | NPC1 (0.42) | ALDH1A1KDM4EL3MBTL1TSHRLMNA | |
| SCHEMBL7439165 | 0.83 | ALDH1A1 (0.47) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL7438639 | 0.82 | ALDH1A1 (0.47) | ALDH1A1CYP1A2KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |