Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11928234 | 0.88 | CHRM2 (0.61) | CHRM2CHRM1LMNAL3MBTL1KMT2A | |
| SCHEMBL7438870 | 0.87 | CHRM2 (0.44) | CHRM2CHRM1LMNAL3MBTL1KMT2A | |
| SCHEMBL4616344 | 0.87 | CHRM2 (0.63) | CHRM2CHRM1LMNAL3MBTL1KMT2A | |
| SCHEMBL7288846 | 0.84 | CHRM2 (0.55) | CHRM2CHRM1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL15797451 | 0.84 | LMNA (0.63) | CHRM2CHRM1LMNAL3MBTL1KMT2A | |
| SCHEMBL7437442 | 0.83 | TSHR (0.45) | CHRM2CHRM1LMNAHSD11B1ALOX5 | |
| SCHEMBL7434817 | 0.81 | LMNA (0.51) | LMNAKMT2AALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL7426489 | 0.81 | CHRM2 (0.38) | CHRM2CHRM1LMNAKMT2AALDH1A1 | |
| SCHEMBL5428037 | 0.80 | CHRM2 (0.54) | CHRM2CHRM1LMNAL3MBTL1CYP2D6 | |
| SCHEMBL7431600 | 0.79 | CHRM2 (0.37) | CHRM2CHRM1KMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |