Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426489 | 0.87 | CHRM2 (0.38) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7437442 | 0.85 | TSHR (0.45) | LMNATSHRNPSR1 | |
| SCHEMBL12486937 | 0.84 | LMNA (0.71) | LMNAGAAALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL12487282 | 0.83 | LMNA (0.74) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3990860 | 0.83 | GAA (0.72) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4418458 | 0.83 | GAA (0.72) | LMNAGAAALDH1A1MEN1KMT2A | |
| SCHEMBL7445606 | 0.82 | ADRA1D (0.41) | LMNAALDH1A1OPRD1OPRM1OPRK1 | |
| SCHEMBL7431600 | 0.81 | CHRM2 (0.37) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7439650 | 0.81 | CHRM2 (0.56) | LMNAALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL7435074 | 0.81 | CA2 (0.41) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |