Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439650 | 0.87 | CHRM2 (0.56) | CHRM2CHRM1TNFCACNA2D1CACNA1B | |
| SCHEMBL7440423 | 0.83 | PDE1A (0.40) | CHRM2CHRM1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL7282340 | 0.83 | ADRB1 (0.46) | CHRM2CHRM1TNFCACNA2D1CACNA1B | |
| SCHEMBL7434643 | 0.78 | CES2 (0.38) | CHRM2CHRM1ALDH1A1 | |
| SCHEMBL7437442 | 0.76 | TSHR (0.45) | CHRM2CHRM1CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL11928234 | 0.75 | CHRM2 (0.61) | CHRM2CHRM1KMT2AL3MBTL1LMNA | |
| SCHEMBL7434817 | 0.74 | LMNA (0.51) | KMT2ALMNAALDH1A1GAA | |
| SCHEMBL7426489 | 0.74 | CHRM2 (0.38) | CHRM2CHRM1KMT2ALMNAALDH1A1 | |
| SCHEMBL4616344 | 0.74 | CHRM2 (0.63) | CHRM2CHRM1KMT2AL3MBTL1LMNA | |
| SCHEMBL7431600 | 0.72 | CHRM2 (0.37) | CHRM2CHRM1KMT2AATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |