Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434817 | 0.87 | LMNA (0.51) | LMNAGAAALDH1A1KMT2AMEN1 | |
| SCHEMBL7437442 | 0.85 | TSHR (0.45) | CHRM2CHRM1LMNATEAD1SMN1; SMN2 | |
| SCHEMBL7439650 | 0.81 | CHRM2 (0.56) | CHRM2CHRM1LMNAALDH1A1KMT2A | |
| SCHEMBL7431600 | 0.81 | CHRM2 (0.37) | CHRM2CHRM1TEAD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7435074 | 0.81 | CA2 (0.41) | CA2 | |
| SCHEMBL7441378 | 0.81 | TEAD1 (0.54) | TEAD1GAAKMT2AMEN1TSHR | |
| SCHEMBL7434257 | 0.80 | EPHX1 (0.40) | CHRM2CHRM1LMNAKMT2ATSHR | |
| SCHEMBL7435526 | 0.79 | CHRM2 (0.36) | CHRM2CHRM1LMNATEAD1GAA | |
| SCHEMBL7431638 | 0.79 | EPHX1 (0.55) | CHRM1LMNATSHRNFKB1 | |
| SCHEMBL7434643 | 0.78 | CES2 (0.38) | CHRM2CHRM1TEAD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4499100-A | CARDIOUVASCULAR DISORDERS | SYNTEX (U.S.A.) INC. (US) | 1985-02-12 | — | — | US | disclosed |