Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.67 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.66 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.50 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10359897 | 0.93 | SLC6A4 (0.62) | SLC6A4HRH3SLC7A5SLC6A9CACNA2D1 | |
| SCHEMBL29700710 | 0.80 | SLC6A4 (1.00) | SLC6A4HRH3SLC7A5SLC6A9SLC6A2 | |
| SCHEMBL679320 | 0.80 | SLC6A4 (1.00) | SLC6A4HRH3SLC7A5SLC6A9SLC6A2 | |
| SCHEMBL13476290 | 0.80 | CACNA2D1 (0.55) | SLC6A4HRH3SLC7A5CACNA2D1SLC6A2 | |
| SCHEMBL17267492 | 0.80 | SLC7A5 (1.00) | SLC6A4HRH3SLC7A5SLC6A2SLC6A3 | |
| SCHEMBL2600190 | 0.80 | CACNA2D1 (0.55) | SLC6A4HRH3SLC7A5CACNA2D1SLC6A2 | |
| Oxalic Acid SCHEMBL10101 | 0.79 | SLC6A9 (0.47) | SLC6A4HRH3SLC7A5SLC6A9CACNA2D1 | |
| Oxalic Acid SCHEMBL3485 | 0.79 | SLC6A9 (0.47) | SLC6A4HRH3SLC7A5SLC6A9CACNA2D1 | |
| SCHEMBL7433161 | 0.79 | SLC6A4 (0.69) | SLC6A4HRH3SLC6A9SLC6A2SLC6A3 | |
| Oxalic Acid SCHEMBL10450 | 0.78 | SLC6A9 (0.48) | SLC6A4HRH3SLC6A9CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0571685-A1 | Aryloxyheteroarylpropylamines, their preparation and use | NOVO NORDISK A/S (DK) | 1993-12-01 | — | — | EP | claimed |
| EP-0571685-A1 | Aryloxyheteroarylpropylamines, their preparation and use | NOVO NORDISK A/S (DK) | 1993-12-01 | — | — | EP | disclosed |