Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7442033 | 0.79 | PKM (0.45) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL7410880 | 0.79 | PDGFRB (0.49) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7436927 | 0.77 | PDE7A (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL7444355 | 0.76 | MAPT (0.55) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL30438628 | 0.76 | ADRB2 (0.65) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL29010814 | 0.76 | ADRB2 (0.65) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL6420733 | 0.76 | MEN1 (0.52) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| Hydrochloric Acid SCHEMBL7433736 | 0.75 | MAPT (0.54) | ALDH1A1KDM4EHPGDMAPTMEN1 | |
| SCHEMBL10886665 | 0.75 | PKM (0.61) | ALDH1A1MAPTMEN1KMT2AMAPK1 | |
| SCHEMBL7427118 | 0.74 | MAPK1 (0.50) | ALDH1A1KDM4EHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322346-A | 5H-2,3-Benzodiazepine derivatives | KOROSI JENO | 1982-03-30 | — | — | US | disclosed |